LATEST PUBLICATIONS
Conca, F., Bayburtlu, D. K., Vismara, M., Surdo, N. C., Tavoni, A., Nogara, L., Sarra, A., Ciciliot, S., Di Benedetto, G., Iannucci, L. F., & Lefkimmiatis, K. (2025). Phosphatases Control the Duration and Range of cAMP/PKA Microdomains. Function (Oxford, England), 6(2), zqaf007. https://doi.org/10.1093/function/zqaf007
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Brunetti, V., Berra-Romani, R., Conca, F., Soda, T., Biella, G. R., Gerbino, A., Moccia, F., & Scarpellino, G. (2024). Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells. Frontiers in physiology, 15, 1426783. https://doi.org/10.3389/fphys.2024.1426783โ
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Noè, R., Inglese, N., Romani, P., Serafini, T., Paoli, C., Calciolari, B., Fantuz, M., Zamborlin, A., Surdo, N. C., Spada, V., Spacci, M., Volta, S., Ermini, M. L., Di Benedetto, G., Frusca, V., Santi, C., Lefkimmiatis, K., Dupont, S., Voliani, V., Sancineto, L., … Carrer, A. (2023). Organic Selenium induces ferroptosis in pancreatic cancer cells. Redox biology, 68, 102962. https://doi.org/10.1016/j.redox.2023.102962
Iannucci, L. F., D'Erchia, A. M., Picardi, E., Bettio, D., Conca, F., Surdo, N. C., Di Benedetto, G., Musso, D., Arrigoni, C., Lolicato, M., Vismara, M., Grisan, F., Salviati, L., Milanesi, L., Pesole, G., & Lefkimmiatis, K. (2023). Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription. Nature communications, 14(1), 5521. https://doi.org/10.1038/s41467-023-41088-x
Li, D., Liu, K., Davis, H., Robertson, C., Neely, O. C., Tarafdar, A., Li, N., Lefkimmiatis, K., Zaccolo, M., & Paterson, D. J. (2022). Abnormal Cyclic Nucleotide Signaling at the Outer Mitochondrial Membrane In Sympathetic Neurons During the Early Stages of Hypertension. Hypertension (Dallas, Tex. : 1979), 79(7), 1374–1384. https://doi.org/10.1161/HYPERTENSIONAHA.121.18882
Faris, P., Rumolo, A., Tapella, L., Tanzi, M., Metallo, A., Conca, F., Negri, S., Lefkimmiatis, K., Pedrazzoli, P., Lim, D., Montagna, D., & Moccia, F. (2022). Store-Operated Ca2+ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients. Cancers, 14(14), 3312. https://doi.org/10.3390/cancers14143312
Regazzo, D., Bertazza, L., Galletta, E., Barollo, S., Mondin, A., Zovato, S., Iacobone, M., Zilio, E., Scaroni, C., Radu, C. M., di Benedetto, G., Mian, C., Lefkimmiatis, K., & Occhi, G. (2022). The GIP/GIPR axis in medullary thyroid cancer: clinical and molecular findings. Endocrine-related cancer, 29(5), 273–284. https://doi.org/10.1530/ERC-21-0258
Pati, R., Palazzo, C., Valente, O., Abbrescia, P., Messina, R., Surdo, N. C., Lefkimmiatis, K., Signorelli, F., Nicchia, G. P., & Frigeri, A. (2022). The Readthrough Isoform AQP4ex Is Constitutively Phosphorylated in the Perivascular Astrocyte Endfeet of Human Brain. Biomolecules, 12(5), 633. https://doi.org/10.3390/biom12050633
Di Benedetto, G., Lefkimmiatis, K., & Pozzan, T. (2021). The basics of mitochondrial cAMP signalling: Where, when, why. Cell calcium, 93, 102320. https://doi.org/10.1016/j.ceca.2020.102320
Di Benedetto, G., Iannucci, L. F., Surdo, N. C., Zanin, S., Conca, F., Grisan, F., Gerbino, A., & Lefkimmiatis, K. (2021). Compartmentalized Signaling in Aging and Neurodegeneration. Cells, 10(2), 464. https://doi.org/10.3390/cells10020464
Grisan, F., Spacci, M., Paoli, C., Costamagna, A., Fantuz, M., Martini, M., Lefkimmiatis, K., & Carrer, A. (2021). Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells. Metabolites, 11(3), 141. https://doi.org/10.3390/metabo11030141
Trevellin, E., Granzotto, M., Host, C., Grisan, F., De Stefani, D., Grinzato, A., Lefkimmiatis, K., Pagano, C., Rizzuto, R., & Vettor, R. (2021). A Novel Loss of Function Melanocortin-4-Receptor Mutation (MC4R-F313Sfs*29) in Morbid Obesity. The Journal of clinical endocrinology and metabolism, 106(3), 736–749. https://doi.org/10.1210/clinem/dgaa885
Lefkimmiatis, K., Grisan, F., Iannucci, L. F., Surdo, N. C., Pozzan, T., & Di Benedetto, G. (2021). Mitochondrial communication in the context of aging. Aging clinical and experimental research, 33(5), 1367–1370. https://doi.org/10.1007/s40520-019-01451-9
Iannucci, L. F., Di Benedetto, G., & Lefkimmiatis, K. (2021). PRKA/PKA signals and autophagy: space matters. Autophagy, 17(6), 1563–1564. https://doi.org/10.1080/15548627.2021.1924501
Westensee, I. N., Brodszkij, E., Qian, X., Marcelino, T. F., Lefkimmiatis, K., & Städler, B. (2021). Mitochondria Encapsulation in Hydrogel-Based Artificial Cells as ATP Producing Subunits. Small (Weinheim an der Bergstrasse, Germany), 17(24), e2007959. https://doi.org/10.1002/smll.202007959
Grisan, F., Iannucci, L. F., Surdo, N. C., Gerbino, A., Zanin, S., Di Benedetto, G., Pozzan, T., & Lefkimmiatis, K. (2021). PKA compartmentalization links cAMP signaling and autophagy. Cell death and differentiation, 28(8), 2436–2449. https://doi.org/10.1038/s41418-021-00761-8

