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LATEST PUBLICATIONS

Conca, F., Bayburtlu, D. K., Vismara, M., Surdo, N. C., Tavoni, A., Nogara, L., Sarra, A., Ciciliot, S., Di Benedetto, G., Iannucci, L. F., & Lefkimmiatis, K. (2025). Phosphatases Control the Duration and Range of cAMP/PKA Microdomains. Function (Oxford, England), 6(2), zqaf007. https://doi.org/10.1093/function/zqaf007

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Brunetti, V., Berra-Romani, R., Conca, F., Soda, T., Biella, G. R., Gerbino, A., Moccia, F., & Scarpellino, G. (2024). Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells. Frontiers in physiology, 15, 1426783. https://doi.org/10.3389/fphys.2024.1426783โ€‹

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Noè, R., Inglese, N., Romani, P., Serafini, T., Paoli, C., Calciolari, B., Fantuz, M., Zamborlin, A., Surdo, N. C., Spada, V., Spacci, M., Volta, S., Ermini, M. L., Di Benedetto, G., Frusca, V., Santi, C., Lefkimmiatis, K., Dupont, S., Voliani, V., Sancineto, L., … Carrer, A. (2023). Organic Selenium induces ferroptosis in pancreatic cancer cells. Redox biology, 68, 102962. https://doi.org/10.1016/j.redox.2023.102962

Iannucci, L. F., D'Erchia, A. M., Picardi, E., Bettio, D., Conca, F., Surdo, N. C., Di Benedetto, G., Musso, D., Arrigoni, C., Lolicato, M., Vismara, M., Grisan, F., Salviati, L., Milanesi, L., Pesole, G., & Lefkimmiatis, K. (2023). Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription. Nature communications, 14(1), 5521. https://doi.org/10.1038/s41467-023-41088-x

Li, D., Liu, K., Davis, H., Robertson, C., Neely, O. C., Tarafdar, A., Li, N., Lefkimmiatis, K., Zaccolo, M., & Paterson, D. J. (2022). Abnormal Cyclic Nucleotide Signaling at the Outer Mitochondrial Membrane In Sympathetic Neurons During the Early Stages of Hypertension. Hypertension (Dallas, Tex. : 1979), 79(7), 1374–1384. https://doi.org/10.1161/HYPERTENSIONAHA.121.18882

Faris, P., Rumolo, A., Tapella, L., Tanzi, M., Metallo, A., Conca, F., Negri, S., Lefkimmiatis, K., Pedrazzoli, P., Lim, D., Montagna, D., & Moccia, F. (2022). Store-Operated Ca2+ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients. Cancers, 14(14), 3312. https://doi.org/10.3390/cancers14143312

Regazzo, D., Bertazza, L., Galletta, E., Barollo, S., Mondin, A., Zovato, S., Iacobone, M., Zilio, E., Scaroni, C., Radu, C. M., di Benedetto, G., Mian, C., Lefkimmiatis, K., & Occhi, G. (2022). The GIP/GIPR axis in medullary thyroid cancer: clinical and molecular findings. Endocrine-related cancer, 29(5), 273–284. https://doi.org/10.1530/ERC-21-0258

Pati, R., Palazzo, C., Valente, O., Abbrescia, P., Messina, R., Surdo, N. C., Lefkimmiatis, K., Signorelli, F., Nicchia, G. P., & Frigeri, A. (2022). The Readthrough Isoform AQP4ex Is Constitutively Phosphorylated in the Perivascular Astrocyte Endfeet of Human Brain. Biomolecules, 12(5), 633. https://doi.org/10.3390/biom12050633

Di Benedetto, G., Lefkimmiatis, K., & Pozzan, T. (2021). The basics of mitochondrial cAMP signalling: Where, when, why. Cell calcium, 93, 102320. https://doi.org/10.1016/j.ceca.2020.102320

Di Benedetto, G., Iannucci, L. F., Surdo, N. C., Zanin, S., Conca, F., Grisan, F., Gerbino, A., & Lefkimmiatis, K. (2021). Compartmentalized Signaling in Aging and Neurodegeneration. Cells, 10(2), 464. https://doi.org/10.3390/cells10020464

Grisan, F., Spacci, M., Paoli, C., Costamagna, A., Fantuz, M., Martini, M., Lefkimmiatis, K., & Carrer, A. (2021). Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells. Metabolites, 11(3), 141. https://doi.org/10.3390/metabo11030141

Trevellin, E., Granzotto, M., Host, C., Grisan, F., De Stefani, D., Grinzato, A., Lefkimmiatis, K., Pagano, C., Rizzuto, R., & Vettor, R. (2021). A Novel Loss of Function Melanocortin-4-Receptor Mutation (MC4R-F313Sfs*29) in Morbid Obesity. The Journal of clinical endocrinology and metabolism, 106(3), 736–749. https://doi.org/10.1210/clinem/dgaa885

Lefkimmiatis, K., Grisan, F., Iannucci, L. F., Surdo, N. C., Pozzan, T., & Di Benedetto, G. (2021). Mitochondrial communication in the context of aging. Aging clinical and experimental research, 33(5), 1367–1370. https://doi.org/10.1007/s40520-019-01451-9 

Iannucci, L. F., Di Benedetto, G., & Lefkimmiatis, K. (2021). PRKA/PKA signals and autophagy: space matters. Autophagy, 17(6), 1563–1564. https://doi.org/10.1080/15548627.2021.1924501

Westensee, I. N., Brodszkij, E., Qian, X., Marcelino, T. F., Lefkimmiatis, K., & Städler, B. (2021). Mitochondria Encapsulation in Hydrogel-Based Artificial Cells as ATP Producing Subunits. Small (Weinheim an der Bergstrasse, Germany), 17(24), e2007959. https://doi.org/10.1002/smll.202007959

Grisan, F., Iannucci, L. F., Surdo, N. C., Gerbino, A., Zanin, S., Di Benedetto, G., Pozzan, T., & Lefkimmiatis, K. (2021). PKA compartmentalization links cAMP signaling and autophagy. Cell death and differentiation, 28(8), 2436–2449. https://doi.org/10.1038/s41418-021-00761-8

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